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Hercules: a profile HMM-based hybrid error correction algorithm for long reads

Choosing whether to use second or third generation sequencing platforms can lead to trade-offs between accuracy and read length. Several types of studies require long and accurate reads. In such cases researchers often combine both technologies and the erroneous long reads are corrected using the sh...

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Detalles Bibliográficos
Autores principales: Firtina, Can, Bar-Joseph, Ziv, Alkan, Can, Cicek, A Ercument
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265270/
https://www.ncbi.nlm.nih.gov/pubmed/30124947
http://dx.doi.org/10.1093/nar/gky724