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Hercules: a profile HMM-based hybrid error correction algorithm for long reads
Choosing whether to use second or third generation sequencing platforms can lead to trade-offs between accuracy and read length. Several types of studies require long and accurate reads. In such cases researchers often combine both technologies and the erroneous long reads are corrected using the sh...
Autores principales: | Firtina, Can, Bar-Joseph, Ziv, Alkan, Can, Cicek, A Ercument |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265270/ https://www.ncbi.nlm.nih.gov/pubmed/30124947 http://dx.doi.org/10.1093/nar/gky724 |
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