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TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

Alzheimer’s disease (AD) is the leading cause of age-related dementia among the elderly population. Recent genetic studies have identified rare variants of the gene encoding the triggering receptor expressed on myeloid cells-2 (TREM2) as significant genetic risk factors in late-onset AD (LOAD). TREM...

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Detalles Bibliográficos
Autores principales: Zheng, Honghua, Cheng, Baoying, Li, Yanfang, Li, Xin, Chen, Xiaofen, Zhang, Yun-wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265312/
https://www.ncbi.nlm.nih.gov/pubmed/30532704
http://dx.doi.org/10.3389/fnagi.2018.00395