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Thy-1 (CD90) Signaling Preferentially Promotes RORγt Expression and a Th17 Response
Thy-1 (CD90) is a glycosylphosphatidylinositol-anchored protein (GPI-AP) with signaling properties that is abundant on mouse T cells. Upon antibody-mediated crosslinking, Thy-1 provides a T cell receptor (TcR)-like signal that is sufficient to drive CD4(+) T cell proliferation and differentiation in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265317/ https://www.ncbi.nlm.nih.gov/pubmed/30533413 http://dx.doi.org/10.3389/fcell.2018.00158 |