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Thy-1 (CD90) Signaling Preferentially Promotes RORγt Expression and a Th17 Response

Thy-1 (CD90) is a glycosylphosphatidylinositol-anchored protein (GPI-AP) with signaling properties that is abundant on mouse T cells. Upon antibody-mediated crosslinking, Thy-1 provides a T cell receptor (TcR)-like signal that is sufficient to drive CD4(+) T cell proliferation and differentiation in...

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Detalles Bibliográficos
Autores principales:	Furlong, Suzanne, Coombs, Melanie R. Power, Ghassemi-Rad, Javad, Hoskin, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265317/ https://www.ncbi.nlm.nih.gov/pubmed/30533413 http://dx.doi.org/10.3389/fcell.2018.00158

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