Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms

The nucleolus, the site for ribosome biogenesis contains hundreds of proteins and several types of RNA. The functions of many non-ribosomal nucleolar proteins are poorly understood, including Surfeit locus protein 6 (SURF6), an essential disordered protein with roles in ribosome biogenesis and cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrolino, Mylene C., Mitrea, Diana M., Michael, J. Robert, Kriwacki, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265330/
https://www.ncbi.nlm.nih.gov/pubmed/30498217
http://dx.doi.org/10.1038/s41467-018-07530-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265330/
https://www.ncbi.nlm.nih.gov/pubmed/30498217
http://dx.doi.org/10.1038/s41467-018-07530-1

Ejemplares similares