Cargando…
Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms
The nucleolus, the site for ribosome biogenesis contains hundreds of proteins and several types of RNA. The functions of many non-ribosomal nucleolar proteins are poorly understood, including Surfeit locus protein 6 (SURF6), an essential disordered protein with roles in ribosome biogenesis and cell...
Autores principales: | Ferrolino, Mylene C., Mitrea, Diana M., Michael, J. Robert, Kriwacki, Richard W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265330/ https://www.ncbi.nlm.nih.gov/pubmed/30498217 http://dx.doi.org/10.1038/s41467-018-07530-1 |
Ejemplares similares
-
Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation
por: Mitrea, Diana M., et al.
Publicado: (2018) -
Phase separation in biology; functional organization of a higher order
por: Mitrea, Diana M., et al.
Publicado: (2016) -
Phase separation underlies interactions of the SARS-CoV-2 nucleocapsid protein with nucleoli
por: Dogra, Priyanka, et al.
Publicado: (2023) -
Exploring Relationships between the Density of Charged Tracts within Disordered Regions and Phase Separation
por: Somjee, Ramiz, et al.
Publicado: (2020) -
Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation
por: Chandra, Bappaditya, et al.
Publicado: (2022)