Evolution of a General RNA-Cleaving FANA Enzyme

The isolation of synthetic genetic polymers (XNAs) with catalytic activity demonstrates that catalysis is not limited to natural biopolymers, but it remains unknown whether such systems can achieve robust catalysis with Michaelis-Menten kinetics. Here, we describe an efficient RNA-cleaving 2’-fluoro...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yajun, Ngor, Arlene K., Nikoomanzar, Ali, Chaput, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265334/
https://www.ncbi.nlm.nih.gov/pubmed/30498223
http://dx.doi.org/10.1038/s41467-018-07611-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265334/
https://www.ncbi.nlm.nih.gov/pubmed/30498223
http://dx.doi.org/10.1038/s41467-018-07611-1

Ejemplares similares