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Evolution of a General RNA-Cleaving FANA Enzyme
The isolation of synthetic genetic polymers (XNAs) with catalytic activity demonstrates that catalysis is not limited to natural biopolymers, but it remains unknown whether such systems can achieve robust catalysis with Michaelis-Menten kinetics. Here, we describe an efficient RNA-cleaving 2’-fluoro...
Autores principales: | Wang, Yajun, Ngor, Arlene K., Nikoomanzar, Ali, Chaput, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265334/ https://www.ncbi.nlm.nih.gov/pubmed/30498223 http://dx.doi.org/10.1038/s41467-018-07611-1 |
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