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MtrA Response Regulator Controls Cell Division and Cell Wall Metabolism and Affects Susceptibility of Mycobacteria to the First Line Antituberculosis Drugs

The biological processes regulated by the essential response regulator MtrA and the growth conditions promoting its activation in Mycobacterium tuberculosis, a slow grower and pathogen, are largely unknown. Here, using a gain-of-function mutant, MtrA(Y 102C), which functions in the absence of the co...

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Detalles Bibliográficos
Autores principales: Gorla, Purushotham, Plocinska, Renata, Sarva, Krishna, Satsangi, Akash T., Pandeeti, Emmanuel, Donnelly, Robert, Dziadek, Jaroslaw, Rajagopalan, Malini, Madiraju, Murty V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265350/
https://www.ncbi.nlm.nih.gov/pubmed/30532747
http://dx.doi.org/10.3389/fmicb.2018.02839