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MtrA Response Regulator Controls Cell Division and Cell Wall Metabolism and Affects Susceptibility of Mycobacteria to the First Line Antituberculosis Drugs
The biological processes regulated by the essential response regulator MtrA and the growth conditions promoting its activation in Mycobacterium tuberculosis, a slow grower and pathogen, are largely unknown. Here, using a gain-of-function mutant, MtrA(Y 102C), which functions in the absence of the co...
Autores principales: | Gorla, Purushotham, Plocinska, Renata, Sarva, Krishna, Satsangi, Akash T., Pandeeti, Emmanuel, Donnelly, Robert, Dziadek, Jaroslaw, Rajagopalan, Malini, Madiraju, Murty V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265350/ https://www.ncbi.nlm.nih.gov/pubmed/30532747 http://dx.doi.org/10.3389/fmicb.2018.02839 |
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