Test-retest reliability and convergent validity of (R)-[(11)C]PK11195 outcome measures without arterial input function

PURPOSE: The PET radioligand (R)-[(11)C]PK11195 is used to quantify the 18-kDa translocator protein (TSPO), a marker for glial activation. Since there is no brain region devoid of TSPO, an arterial input function (AIF) is ideally required for quantification of binding. However, obtaining an AIF is e...

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Detalles Bibliográficos
Autores principales: Plavén-Sigray, Pontus, Matheson, Granville James, Cselényi, Zsolt, Jucaite, Aurelija, Farde, Lars, Cervenka, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265355/
https://www.ncbi.nlm.nih.gov/pubmed/30498919
http://dx.doi.org/10.1186/s13550-018-0455-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265355/
https://www.ncbi.nlm.nih.gov/pubmed/30498919
http://dx.doi.org/10.1186/s13550-018-0455-8

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