Cargando…
Test-retest reliability and convergent validity of (R)-[(11)C]PK11195 outcome measures without arterial input function
PURPOSE: The PET radioligand (R)-[(11)C]PK11195 is used to quantify the 18-kDa translocator protein (TSPO), a marker for glial activation. Since there is no brain region devoid of TSPO, an arterial input function (AIF) is ideally required for quantification of binding. However, obtaining an AIF is e...
Autores principales: | Plavén-Sigray, Pontus, Matheson, Granville James, Cselényi, Zsolt, Jucaite, Aurelija, Farde, Lars, Cervenka, Simon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265355/ https://www.ncbi.nlm.nih.gov/pubmed/30498919 http://dx.doi.org/10.1186/s13550-018-0455-8 |
Ejemplares similares
-
Kinetic analysis and test-retest variability of the radioligand [(11)C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects
por: Jučaite, Aurelija, et al.
Publicado: (2012) -
Assessment of simplified ratio-based approaches for quantification of PET [(11)C]PBR28 data
por: Matheson, Granville J., et al.
Publicado: (2017) -
[(11)C]SCH23390 binding to the D(1)-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis
por: Stenkrona, Per, et al.
Publicado: (2018) -
Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study
por: Plavén-Sigray, Pontus, et al.
Publicado: (2018) -
Kinfitr — an open-source tool for reproducible PET modelling: validation and evaluation of test-retest reliability
por: Tjerkaski, Jonathan, et al.
Publicado: (2020)