The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity

Mechanosensory hair cells of the inner ear transduce auditory and vestibular sensory input. Hair cells are susceptible to death from a variety of stressors, including treatment with therapeutic drugs that have ototoxic side effects. There is a need for co-therapies to mitigate drug-induced ototoxici...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryals, Matthew, Morell, Robert J., Martin, Daniel, Boger, Erich T., Wu, Patricia, Raible, David W., Cunningham, Lisa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265442/
https://www.ncbi.nlm.nih.gov/pubmed/30532693
http://dx.doi.org/10.3389/fncel.2018.00445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265442/
https://www.ncbi.nlm.nih.gov/pubmed/30532693
http://dx.doi.org/10.3389/fncel.2018.00445

Ejemplares similares