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The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity
Mechanosensory hair cells of the inner ear transduce auditory and vestibular sensory input. Hair cells are susceptible to death from a variety of stressors, including treatment with therapeutic drugs that have ototoxic side effects. There is a need for co-therapies to mitigate drug-induced ototoxici...
Autores principales: | Ryals, Matthew, Morell, Robert J., Martin, Daniel, Boger, Erich T., Wu, Patricia, Raible, David W., Cunningham, Lisa L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265442/ https://www.ncbi.nlm.nih.gov/pubmed/30532693 http://dx.doi.org/10.3389/fncel.2018.00445 |
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