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Single-cell stabilization method identifies gonadotrope transcriptional dynamics and pituitary cell type heterogeneity
Immediate-early response genes (IEGs) are rapidly and transiently induced following an extracellular signal. Elucidating the IEG response patterns in single cells (SCs) requires assaying large numbers of timed samples at high accuracy while minimizing handling effects. To achieve this, we developed...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265460/ https://www.ncbi.nlm.nih.gov/pubmed/30357357 http://dx.doi.org/10.1093/nar/gky991 |