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CLIPick: a sensitive peak caller for expression-based deconvolution of HITS-CLIP signals

High-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP, also called CLIP-Seq) has been used to map global RNA–protein interactions. However, a critical caveat of HITS-CLIP results is that they contain non-linear background noise—different extent of non-specific in...

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Detalles Bibliográficos
Autores principales: Park, Sihyung, Ahn, Seung Hyun, Cho, Eun Sol, Cho, You Kyung, Jang, Eun-Sook, Chi, Sung Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265468/
https://www.ncbi.nlm.nih.gov/pubmed/30329090
http://dx.doi.org/10.1093/nar/gky917