Modular 5′-UTR hexamers for context-independent tuning of protein expression in eukaryotes

Functional characterization of regulatory DNA elements in broad genetic contexts is a prerequisite for forward engineering of biological systems. Translation initiation site (TIS) sequences are attractive to use for regulating gene activity and metabolic pathway fluxes because the genetic changes ar...

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Detalles Bibliográficos
Autores principales: Petersen, Søren D, Zhang, Jie, Lee, Jae S, Jakočiūnas, Tadas, Grav, Lise M, Kildegaard, Helene F, Keasling, Jay D, Jensen, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265478/
https://www.ncbi.nlm.nih.gov/pubmed/30124898
http://dx.doi.org/10.1093/nar/gky734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265478/
https://www.ncbi.nlm.nih.gov/pubmed/30124898
http://dx.doi.org/10.1093/nar/gky734

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