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Modular 5′-UTR hexamers for context-independent tuning of protein expression in eukaryotes
Functional characterization of regulatory DNA elements in broad genetic contexts is a prerequisite for forward engineering of biological systems. Translation initiation site (TIS) sequences are attractive to use for regulating gene activity and metabolic pathway fluxes because the genetic changes ar...
Autores principales: | Petersen, Søren D, Zhang, Jie, Lee, Jae S, Jakočiūnas, Tadas, Grav, Lise M, Kildegaard, Helene F, Keasling, Jay D, Jensen, Michael K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265478/ https://www.ncbi.nlm.nih.gov/pubmed/30124898 http://dx.doi.org/10.1093/nar/gky734 |
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