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NMR structure of a G-quadruplex formed by four d(G(4)C(2)) repeats: insights into structural polymorphism
Most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), is a largely increased number of d(G(4)C(2))n•(G(2)C(4))n repeats located in the non-coding region of C9orf72 gene. Non-canonical structures, including G-quadruplexes, formed within expanded repeats...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265483/ https://www.ncbi.nlm.nih.gov/pubmed/30277522 http://dx.doi.org/10.1093/nar/gky886 |