Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers

Enhancers are distal cis-regulatory elements that modulate gene expression. They are depleted of nucleosomes and enriched in specific histone modifications; thus, calling DNase-seq and histone mark ChIP-seq peaks can predict enhancers. We evaluated nine peak-calling algorithms for predicting enhance...

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Detalles Bibliográficos
Autores principales: Fu, Shaliu, Wang, Qin, Moore, Jill E, Purcaro, Michael J, Pratt, Henry E, Fan, Kaili, Gu, Cuihua, Jiang, Cizhong, Zhu, Ruixin, Kundaje, Anshul, Lu, Aiping, Weng, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265487/
https://www.ncbi.nlm.nih.gov/pubmed/30137428
http://dx.doi.org/10.1093/nar/gky753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265487/
https://www.ncbi.nlm.nih.gov/pubmed/30137428
http://dx.doi.org/10.1093/nar/gky753

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