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Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers
Enhancers are distal cis-regulatory elements that modulate gene expression. They are depleted of nucleosomes and enriched in specific histone modifications; thus, calling DNase-seq and histone mark ChIP-seq peaks can predict enhancers. We evaluated nine peak-calling algorithms for predicting enhance...
Autores principales: | Fu, Shaliu, Wang, Qin, Moore, Jill E, Purcaro, Michael J, Pratt, Henry E, Fan, Kaili, Gu, Cuihua, Jiang, Cizhong, Zhu, Ruixin, Kundaje, Anshul, Lu, Aiping, Weng, Zhiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265487/ https://www.ncbi.nlm.nih.gov/pubmed/30137428 http://dx.doi.org/10.1093/nar/gky753 |
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