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Enhanced transfection of a macromolecular lignin-based DNA complex with low cellular toxicity

Cationic polymers remain attractive tools for non-viral gene transfer. The effectiveness of these vectors rely on the ability to deliver plasmid DNA (pDNA) into the nucleus of cells. While we have previously demonstrated the potential of Lignin-PGEA-PEGMA as a non-viral gene delivery vector, alterat...

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Detalles Bibliográficos
Autores principales: Ho, Yoon Khei, Kai, Dan, Tu, Geraldine Xue En, Deen, G. Roshan, Too, Heng Phon, Loh, Xian Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265617/
https://www.ncbi.nlm.nih.gov/pubmed/30413612
http://dx.doi.org/10.1042/BSR20181021