Large-Scale Analyses of Site-Specific Evolutionary Rates across Eukaryote Proteomes Reveal Confounding Interactions between Intrinsic Disorder, Secondary Structure, and Functional Domains

Various structural and functional constraints govern the evolution of protein sequences. As a result, the relative rates of amino acid replacement among sites within a protein can vary significantly. Previous large-scale work on Metazoan (Animal) protein sequence alignments indicated that amino acid...

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Detalles Bibliográficos
Autores principales: Ahrens, Joseph B., Rahaman, Jordon, Siltberg-Liberles, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265720/
https://www.ncbi.nlm.nih.gov/pubmed/30441862
http://dx.doi.org/10.3390/genes9110553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265720/
https://www.ncbi.nlm.nih.gov/pubmed/30441862
http://dx.doi.org/10.3390/genes9110553

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