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Large-Scale Analyses of Site-Specific Evolutionary Rates across Eukaryote Proteomes Reveal Confounding Interactions between Intrinsic Disorder, Secondary Structure, and Functional Domains

Various structural and functional constraints govern the evolution of protein sequences. As a result, the relative rates of amino acid replacement among sites within a protein can vary significantly. Previous large-scale work on Metazoan (Animal) protein sequence alignments indicated that amino acid...

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Detalles Bibliográficos
Autores principales:	Ahrens, Joseph B., Rahaman, Jordon, Siltberg-Liberles, Jessica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265720/ https://www.ncbi.nlm.nih.gov/pubmed/30441862 http://dx.doi.org/10.3390/genes9110553

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