SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors

SS1P is an anti-mesothelin immunotoxin composed of a targeting antibody fragment genetically fused to a truncated fragment of Pseudomonas exotoxin A. Delayed responses reported in mesothelioma patients receiving SS1P suggest that anti-tumor immunity is induced. The goal of this study is to evaluate...

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Detalles Bibliográficos
Autores principales: Leshem, Yasmin, King, Emily M., Mazor, Ronit, Reiter, Yoram, Pastan, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265743/
https://www.ncbi.nlm.nih.gov/pubmed/30441807
http://dx.doi.org/10.3390/toxins10110470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265743/
https://www.ncbi.nlm.nih.gov/pubmed/30441807
http://dx.doi.org/10.3390/toxins10110470

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