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Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech Poecilobdella manillensis

Antistasin, first identified as a potent inhibitor of the blood coagulation factor Xa, is a novel family of serine protease inhibitors. In this study, we purified a novel antistasin-type inhibitor from leech Poecilobdella manillensis called poecistasin. Amino acid sequencing of this 48-amino-acid pr...

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Detalles Bibliográficos
Autores principales: Tang, Xiaopeng, Chen, Mengrou, Duan, Zilei, Mwangi, James, Li, Pengpeng, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265900/
https://www.ncbi.nlm.nih.gov/pubmed/30373118
http://dx.doi.org/10.3390/toxins10110429