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Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, Ank(GAG)1D4, showed a negative effect on the viral assembly of the HIV-1(NL4-3) laboratory strain. To extend its potential for f...

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Detalles Bibliográficos
Autores principales: Sakkhachornphop, Supachai, Hadpech, Sudarat, Wisitponchai, Tanchanok, Panto, Chansunee, Kantamala, Doungnapa, Utaipat, Utaiwan, Praparattanapan, Jutarat, Kotarathitithum, Wilai, Taejaroenkul, Sineenart, Yasamut, Umpa, Chupradit, Koollawat, Moonmuang, Sutpirat, Sanghiran Lee, Vannajan, Suparatpinyo, Khuanchai, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265948/
https://www.ncbi.nlm.nih.gov/pubmed/30428529
http://dx.doi.org/10.3390/v10110625