Targeted Therapy-Resistant Melanoma Cells Acquire Transcriptomic Similarities with Human Melanoblasts

The mechanisms of adaptive and acquired drug resistance in tumors are not completely understood. So far, gene amplifications or mutations, leading to the reactivation of the MAPK or PI3K pathways have been described. In this study, we used two different methods to generate human melanoblasts: (1) vi...

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Detalles Bibliográficos
Autores principales: Larribère, Lionel, Kuphal, Silke, Sachpekidis, Christos, Sachindra, Hüser, Laura, Bosserhoff, Anja, Utikal, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265976/
https://www.ncbi.nlm.nih.gov/pubmed/30453548
http://dx.doi.org/10.3390/cancers10110451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265976/
https://www.ncbi.nlm.nih.gov/pubmed/30453548
http://dx.doi.org/10.3390/cancers10110451

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