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Comprehensive Analysis of Hepatitis B Virus Promoter Region Mutations

Over 250 million people are infected chronically with hepatitis B virus (HBV), the leading cause of liver cancer worldwide. HBV persists, due, in part, to its compact, stable minichromosome, the covalently-closed, circular DNA (cccDNA), which resides in the hepatocytes’ nuclei. Current therapies tar...

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Detalles Bibliográficos
Autores principales: Meier-Stephenson, Vanessa, Bremner, William T. R., Dalton, Chimone S., van Marle, Guido, Coffin, Carla S., Patel, Trushar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265984/
https://www.ncbi.nlm.nih.gov/pubmed/30388827
http://dx.doi.org/10.3390/v10110603