A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice

H9N2 avian influenza viruses are present in poultry worldwide. These viruses are considered to have pandemic potential, because recent isolates can recognize human-type receptor and several sporadic human infections have been reported. In this study, we aimed to identify mutations related to mammali...

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Detalles Bibliográficos
Autores principales: Kamiki, Haruhiko, Matsugo, Hiromichi, Kobayashi, Tomoya, Ishida, Hiroho, Takenaka-Uema, Akiko, Murakami, Shin, Horimoto, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266086/
https://www.ncbi.nlm.nih.gov/pubmed/30463209
http://dx.doi.org/10.3390/v10110653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266086/
https://www.ncbi.nlm.nih.gov/pubmed/30463209
http://dx.doi.org/10.3390/v10110653

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