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Optimized protocol for detection of native, full‐length HIV‐1 envelope on the surface of transfected cells

AIMS: Designing therapeutics against the HIV envelope glycoprotein (Env) is only as accurate as the structure of the Env they are targeting. Conserving the structure of the Env trimer is crucial for proper experimental assessment of antibody binding and neutralization. However, Env is notably diffic...

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Detalles Bibliográficos
Autores principales: Altman, J.B., Liu, X., Itri, V., Zolla‐Pazner, S., Powell, R.L.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266377/
https://www.ncbi.nlm.nih.gov/pubmed/30623097
http://dx.doi.org/10.1002/hsr2.74