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Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000–300,000 individuals yearly in western Africa and frequently causes lethal disease. Currently, no LASV-specific antivirals or vaccines are commercially available for prevention or treatment of Lassa fever, the disease caused by LASV....

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Detalles Bibliográficos
Autores principales: Caì, Yíngyún, Iwasaki, Masaharu, Beitzel, Brett F., Yú, Shuīqìng, Postnikova, Elena N., Cubitt, Beatrice, DeWald, Lisa Evans, Radoshitzky, Sheli R., Bollinger, Laura, Jahrling, Peter B., Palacios, Gustavo F., de la Torre, Juan C., Kuhn, Jens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266387/
https://www.ncbi.nlm.nih.gov/pubmed/30463334
http://dx.doi.org/10.3390/v10110655