A Pharmacogenetic Study of VDR fok1 and TYMS Polymorphisms and Their Association With Glucocorticoid-Induced Osteonecrosis in Egyptian Children With Acute Lymphoblastic Leukemia

Purpose: Osteonecrosis is a significant toxicity resulting from the treatment of pediatric Acute Lymphoblastic Leukemia (ALL). This study aimed to investigate the relationship between vitamin D receptor fok1 (VDR fok1) and thymidylate synthase (TYMS) gene polymorphisms with the glucocorticoid (GC) i...

Descripción completa

Detalles Bibliográficos
Autores principales: ElHarouni, Dina, Yassin, Dina, Ali, Nesreen, Gohar, Seham, Zaky, Iman, Adwan, Hassan, Sidhom, Iman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266501/
https://www.ncbi.nlm.nih.gov/pubmed/30533396
http://dx.doi.org/10.3389/fonc.2018.00541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266501/
https://www.ncbi.nlm.nih.gov/pubmed/30533396
http://dx.doi.org/10.3389/fonc.2018.00541

Ejemplares similares