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A Pharmacogenetic Study of VDR fok1 and TYMS Polymorphisms and Their Association With Glucocorticoid-Induced Osteonecrosis in Egyptian Children With Acute Lymphoblastic Leukemia

Purpose: Osteonecrosis is a significant toxicity resulting from the treatment of pediatric Acute Lymphoblastic Leukemia (ALL). This study aimed to investigate the relationship between vitamin D receptor fok1 (VDR fok1) and thymidylate synthase (TYMS) gene polymorphisms with the glucocorticoid (GC) i...

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Detalles Bibliográficos
Autores principales:	ElHarouni, Dina, Yassin, Dina, Ali, Nesreen, Gohar, Seham, Zaky, Iman, Adwan, Hassan, Sidhom, Iman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266501/ https://www.ncbi.nlm.nih.gov/pubmed/30533396 http://dx.doi.org/10.3389/fonc.2018.00541

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