Intronic miR-744 Inhibits Glioblastoma Migration by Functionally Antagonizing Its Host Gene MAP2K4

Background: The second intron of Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4), an important hub in the pro-invasive MAPK pathway, harbors miR-744. There is accumulating evidence that intronic micro-RNAs (miRNAs) are capable of either supporting or restraining functional pathways of their host...

Descripción completa

Detalles Bibliográficos
Autores principales: Hübner, Max, Hinske, Christian Ludwig, Effinger, David, Wu, Tingting, Thon, Niklas, Kreth, Friedrich-Wilhelm, Kreth, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266622/
https://www.ncbi.nlm.nih.gov/pubmed/30366472
http://dx.doi.org/10.3390/cancers10110400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266622/
https://www.ncbi.nlm.nih.gov/pubmed/30366472
http://dx.doi.org/10.3390/cancers10110400

Ejemplares similares