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Intronic miR-744 Inhibits Glioblastoma Migration by Functionally Antagonizing Its Host Gene MAP2K4
Background: The second intron of Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4), an important hub in the pro-invasive MAPK pathway, harbors miR-744. There is accumulating evidence that intronic micro-RNAs (miRNAs) are capable of either supporting or restraining functional pathways of their host...
Autores principales: | Hübner, Max, Hinske, Christian Ludwig, Effinger, David, Wu, Tingting, Thon, Niklas, Kreth, Friedrich-Wilhelm, Kreth, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266622/ https://www.ncbi.nlm.nih.gov/pubmed/30366472 http://dx.doi.org/10.3390/cancers10110400 |
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