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Site-Specific N-Glycosylation on the AAV8 Capsid Protein

Adeno associated virus (AAV) is a versatile gene delivery tool, which has been approved as a human gene therapy vector for combating genetic diseases. AAV capsid proteins are the major components that determine the tissue specificity, immunogenicity and in vivo transduction performance of the vector...

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Detalles Bibliográficos
Autores principales: Aloor, Arya, Zhang, Junping, Gashash, Ebtesam A., Parameswaran, Aishwarya, Chrzanowski, Matthew, Ma, Cheng, Diao, Yong, Wang, Peng George, Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266768/
https://www.ncbi.nlm.nih.gov/pubmed/30453606
http://dx.doi.org/10.3390/v10110644