Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus

Immunosuppressed individuals can shed influenza virus for prolonged periods of time, leading to the frequent emergence of antiviral resistance. We evaluated the benefits of oseltamivir and favipiravir combination therapy compared to single antiviral agents and monitored the emergence of drug-resista...

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Detalles Bibliográficos
Autores principales: Baz, Mariana, Carbonneau, Julie, Rhéaume, Chantal, Cavanagh, Marie-Hélène, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266789/
https://www.ncbi.nlm.nih.gov/pubmed/30400276
http://dx.doi.org/10.3390/v10110610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266789/
https://www.ncbi.nlm.nih.gov/pubmed/30400276
http://dx.doi.org/10.3390/v10110610

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