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Distinguishing crystallographic from biological interfaces in protein complexes: role of intermolecular contacts and energetics for classification

BACKGROUND: Study of macromolecular assemblies is fundamental to understand functions in cells. X-ray crystallography is the most common technique to solve their 3D structure at atomic resolution. In a crystal, however, both biologically-relevant interfaces and non-specific interfaces resulting from...

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Detalles Bibliográficos
Autores principales: Elez, Katarina, Bonvin, Alexandre M. J. J., Vangone, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266931/
https://www.ncbi.nlm.nih.gov/pubmed/30497368
http://dx.doi.org/10.1186/s12859-018-2414-9