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Distinguishing crystallographic from biological interfaces in protein complexes: role of intermolecular contacts and energetics for classification
BACKGROUND: Study of macromolecular assemblies is fundamental to understand functions in cells. X-ray crystallography is the most common technique to solve their 3D structure at atomic resolution. In a crystal, however, both biologically-relevant interfaces and non-specific interfaces resulting from...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266931/ https://www.ncbi.nlm.nih.gov/pubmed/30497368 http://dx.doi.org/10.1186/s12859-018-2414-9 |