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Efficient computation of spaced seed hashing with block indexing

BACKGROUND: Spaced-seeds, i.e. patterns in which some fixed positions are allowed to be wild-cards, play a crucial role in several bioinformatics applications involving substrings counting and indexing, by often providing better sensitivity with respect to k-mers based approaches. K-mers based appro...

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Detalles Bibliográficos
Autores principales: Girotto, Samuele, Comin, Matteo, Pizzi, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266934/
https://www.ncbi.nlm.nih.gov/pubmed/30497364
http://dx.doi.org/10.1186/s12859-018-2415-8