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Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition

Overexpression of the MYC oncogene is a key feature of many human malignancies including Burkitt lymphoma. While MYC is widely regarded to be a promising therapeutic target, a clinically effective MYC inhibitor is still elusive. Here, we report an alternative strategy, targeting MYC indirectly throu...

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Detalles Bibliográficos
Autores principales: Poole, Candace J., Zheng, Wenli, Lee, Haesung, Young, Danielle, Lodh, Atul, Chadli, Ahmed, van Riggelen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266960/
https://www.ncbi.nlm.nih.gov/pubmed/30453475
http://dx.doi.org/10.3390/cancers10110448