TGFβ Imprinting During Activation Promotes Natural Killer Cell Cytokine Hypersecretion

Transforming growth factor-beta (TGFβ) is a potent immunosuppressive cytokine that inhibits the anti-tumor responses of NK cells and T cells. However, the stimulation of natural killer (NK) cells with pro-inflammatory cytokines decreases NK cell sensitivity to TGFβ. Herein, we sought to determine if...

Descripción completa

Detalles Bibliográficos
Autores principales: Foltz, Jennifer A., Moseman, Jena E., Thakkar, Aarohi, Chakravarti, Nitin, Lee, Dean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267005/
https://www.ncbi.nlm.nih.gov/pubmed/30400618
http://dx.doi.org/10.3390/cancers10110423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267005/
https://www.ncbi.nlm.nih.gov/pubmed/30400618
http://dx.doi.org/10.3390/cancers10110423

Ejemplares similares