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TGFβ Imprinting During Activation Promotes Natural Killer Cell Cytokine Hypersecretion

Transforming growth factor-beta (TGFβ) is a potent immunosuppressive cytokine that inhibits the anti-tumor responses of NK cells and T cells. However, the stimulation of natural killer (NK) cells with pro-inflammatory cytokines decreases NK cell sensitivity to TGFβ. Herein, we sought to determine if...

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Detalles Bibliográficos
Autores principales:	Foltz, Jennifer A., Moseman, Jena E., Thakkar, Aarohi, Chakravarti, Nitin, Lee, Dean A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267005/ https://www.ncbi.nlm.nih.gov/pubmed/30400618 http://dx.doi.org/10.3390/cancers10110423

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