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Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation

Glioblastoma is the most common malignant brain tumour in adults. The failure of current therapies can be ascribed to glioma stem cells (GSCs), which can rapidly repopulate the tumour following the initial treatment. The study of histone deacetylase inhibitors, such as valproic acid (VPA), is becomi...

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Detalles Bibliográficos
Autores principales: Riva, Gabriele, Cilibrasi, Chiara, Bazzoni, Riccardo, Cadamuro, Massimiliano, Negroni, Caterina, Butta, Valentina, Strazzabosco, Mario, Dalprà, Leda, Lavitrano, Marialuisa, Bentivegna, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267016/
https://www.ncbi.nlm.nih.gov/pubmed/30373123
http://dx.doi.org/10.3390/genes9110522