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Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies

BACKGROUND: Recent developments in third-gen long read sequencing and diploid-aware assemblers have resulted in the rapid release of numerous reference-quality assemblies for diploid genomes. However, assembly of highly heterozygous genomes is still problematic when regional heterogeneity is so high...

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Detalles Bibliográficos
Autores principales: Roach, Michael J., Schmidt, Simon A., Borneman, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267036/
https://www.ncbi.nlm.nih.gov/pubmed/30497373
http://dx.doi.org/10.1186/s12859-018-2485-7