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Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

BACKGROUND: The presence of hypoxic areas is common in all breast lesions but no data clearly correlate low oxygenation with the acquisition of malignant features by non-invasive cells, particularly by cells from ductal carcinoma in situ (DCIS), the most frequently diagnosed tumor in women. METHODS:...

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Detalles Bibliográficos
Autores principales: Al-Qassab, Yasamin, Grassilli, Silvia, Brugnoli, Federica, Vezzali, Federica, Capitani, Silvano, Bertagnolo, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267073/
https://www.ncbi.nlm.nih.gov/pubmed/30497437
http://dx.doi.org/10.1186/s12885-018-5038-6