miRNA Mediated Noise Making of 3′UTR Mutations in Cancer

Somatic mutations in 3′-untranslated regions (3′UTR) do not alter amino acids and are considered to be silent in cancers. We found that such mutations can promote tumor progression by altering microRNA (miRNA) targeting efficiency and consequently affecting miRNA–mRNA interactions. We identified 67,...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Wu, Lingxiang, Zhu, Mengyan, Wang, Ziyu, Wu, Min, Li, Pengping, Nie, Yumin, Lin, Xue, Hu, Jie, Eskilsson, Eskil, Wang, Qh, Shao, Jiaofang, Lyu, Sali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267165/
https://www.ncbi.nlm.nih.gov/pubmed/30424545
http://dx.doi.org/10.3390/genes9110545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267165/
https://www.ncbi.nlm.nih.gov/pubmed/30424545
http://dx.doi.org/10.3390/genes9110545

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