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RNA Virus Fidelity Mutants: A Useful Tool for Evolutionary Biology or a Complex Challenge?

RNA viruses replicate with low fidelity due to the error-prone nature of the RNA-dependent RNA polymerase, which generates approximately one mutation per round of genome replication. Due to the large population sizes produced by RNA viruses during replication, this results in a cloud of closely rela...

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Detalles Bibliográficos
Autores principales: Kautz, Tiffany F., Forrester, Naomi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267201/
https://www.ncbi.nlm.nih.gov/pubmed/30388745
http://dx.doi.org/10.3390/v10110600